Anxiety/ Depression/ PTSD

“In his hand is the life of every creature and the breath of all mankind.”   Job 12:10

Depression can be mild to severe, ranging from sleeping more to suicidal thoughts. Causes include: chronic stress, nutritional deficiencies, sugar and processed junk foods, allergies, illness, thyroid imbalance, lack of sunlight, and certain drugs. Diet is critical; high intake of sugar and fat cause fatigue and sluggish circulation. A balance of complex carbohydrates and proteins is most appropriate to maintain alertness with a quiet ease. Contrary to the popular misconceptions about Anxiety Disorders today, Anxiety Disorder is not a purely biochemical or medical disorder. Currently there are three main schools of thought regarding the etiology of Anxiety Disorders: The Biological Theory, (includes the genetic predisposition in panic disorder and presupposes a chemical imbalance in the brain), The Psycho-dynamic Theory (looks at childhood issues as being the cause), and the Behavioral Theory (sees the cause as learned behavior, including our negative thought patterns). (Fox, Barker 1997) Anxiety Disorders include the following specific disorders: Anxiety Disorder with or without Agoraphobia, Agoraphobia without History of Panic Disorder, Specific Phobia, Social Phobia, Obsessive-Compulsive Disorder, Post-traumatic Stress Disorder, Acute Stress Disorder, Generalized Anxiety Disorder, Anxiety Disorder Due To a General Medical Condition, Substance-Induced Anxiety Disorder, and Anxiety Disorder Not Otherwise Specified. Of this list there are five major Anxiety Disorders, which are; Panic Disorder, Social Anxiety Disorder, Post-traumatic Stress Disorder, Obsessive-Compulsive Disorder, and Generalized Anxiety Disorder.

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Scientists Say They’ve Identified The Physical Source of Depression in The Brain

Depression isn’t just ‘all in your head’.

 
PETER DOCKRILL
19 OCT 2016
 

The region of the brain that serves as the physical source of feelings of depression has been identified, with new MRI data being the latest evidence to show that depression isn’t just a ‘frame of mind’.

Scientists have scanned the brains of more than 900 people, and the results suggest that feelings of loss and low self-esteem are tied to the functioning of the orbitofrontal cortex – a region of the brain associated with sensory integration, expectation, and decision-making.

 

“Our finding, with the combination of big data we collected around the world and our novel methods, enables us to locate the roots of depression, which should open up new avenues for better therapeutic treatments in the near future for this horrible disease,” says computational psychiatrist Jianfeng Feng from the University of Warwick in the UK and Fudan University in China.

To isolate the brain mechanisms involved in depression, Feng’s team recruited 909 people in China to take part in MRI brain scans. Of this group, 421 of the participants had been diagnosed with major depressive disorder (aka depression). The remaining 488 participants – who didn’t have depression – acted as a control group.

The scans showed that depression is related to the neural activity of two different portions of the orbitofrontal cortex (OFC): the medial OFC and lateral OFC.

The medial OFC becomes active when we receive rewards. In other words, when something good happens, the medial OFC fires up, and we feel good about it.

But the researchers found that the participants with depression showed weaker neural connections between the medial OFC and the brain’s memory systems in the hippocampus.

It’s not yet clear what the implications of this are, but it could mean that people with depression have a harder time accessing and recalling happy or positive memories.

 

In addition to displaying weaker connections with the medial OFC, depression patients in the study also showed stronger neural connections around the lateral OFC – which is involved with processing non-reward outcomes, such as punishments.

These stronger connections were made with parts of the brain including the precuneus – thought to be involved with our sense of self – and the angular gyrus, which is responsible for memory retrieval and attention.

All of which suggests that the heightened brain activity around the lateral OFC could mean that people with depression find it easier to relive negative experiences and harder to feel good about themselves.

Meanwhile, these effects seem to be compounded by the reduced medial OFC connectivity, which makes it harder for them to process happy memories. The worst of both worlds, so to speak.

When contrasting the neural activity of the depression patients who were taking medication for their condition with the neural activity of depression patients not on medication, the researchers found that the functional connectivity of the lateral OFC – processing non-reward outcomes like punishments – was lower in those who were medicated.

This suggests that existing antidepressants do have a positive effect in evening out these mechanisms in this part of the brain.

2395872938-depression-2University of Warwick

A better understanding of the underlying physical causes of depression could make a huge difference in how we fight the disease, because the current treatment method – trying one medication after another until something sticks – isn’t effective, with roughly 50 percent of all first-time prescriptions failing to help those in need.

So on top of being further evidence that depression – and mental illness in general – is not just a frame of mind, the research could lead to new personalised medications that specifically target the orbitofrontal cortex and its two sub-regions for more effective relief.

The findings are reported in Brain.

 

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1324 Nervous TensionThis compound is a Nervine, Sedative, Anti-Spasmodic and Tonic. It helps to soothe the nervous system. It also relieves stress, tension and anxiety. It can be used for any nervous condition. It also calms seizures, convulsions and relaxes the nerves.

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  • Twitter28

    Hi, just wanted to say i liked this article.

  • admin

    Thank you very much! Brittney Haywood for publishing my work

    I am working very hard to produce a lot more information to help educate and bring comfort to everyone!

    I pray with everyone while I do FREE consultations for anyone who has questions on any health related issues or just simply trying to live a more healthy natural life.
    You can call me at my home number 1-503-362-5899 and email truman@healthherbs.com

    May the Grace of our Lord Jesus Christ, the love of God, and the sweet
    fellowship of the Holy Spirit be with you now and forever more, Amen.

    Dr. Truman Berst