Sarcoidosis

Sarcoidosis Natural Remedies

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Sarcoidosis treatment, diet, food, review of cause and natural, alternative therapy by Ray Sahelian, M.D. see a list of hundreds of health and nutrition topics
February 10 2016

Sarcoidosis is a systemic granulomatous disease of unknown cause characterized by the formation of noncaseating granulomas. Sarcoidosis primarily involves inflammation that produces tiny lumps of cells in various organs. The lumps are called granulomas because they look like grains of sugar or sand. They are very small and can be seen only with a microscope. These tiny granulomas, over time, enlarge and join each other. If many granulomas form in an organ, they can affect how the organ works. This leads to the symptoms and diagnosis of sarcoidosis. Any organ can be affected, but most often sarcoidosis affects the lungs and lymph nodes.
Sarcoidosis is thought by most scientists to be a disorder of the immune system, where the body’s natural defense system malfunctions.

Cause of sarcoidosis
This medical disease may be linked to seasonal, environmental and genetic factors. Another cause may be infection, due to mycobacterial or other infections. Some drugs may be another cause.
   Is pollution or exposure to dust and particles another cause? There is an increased incidence of sarcoidosis or “sarcoid-like” granulomatous pulmonary disease among Fire Department of New York rescue workers since the World Trade Center disaster. On September 11, 2001, the attack and collapse of the World Trade Center in New York City released large amounts of airborne particulate matter and combustion byproducts.. Since then, an increased risk of granulomatous pneumonitis and cardiopulmonary sarcoidosis in workers exposed to dust have been reported.

Diet
In some cases sarcoidosis has been associated with celiac disease, such as a reaction to certain protein chains commonly referred to as glutens found in some cereal grains.

Natural supplements, herbs, vitamins
I was diagnosed with sarcoidosis 5 years ago and am having some neuro symptoms now and lung symptoms have started to return. I ran across this piece of news out of Johns Hopkins about amyloids being very high in sarcoidosis cells. In light of their discovery wouldn’t it be safe to say that looking at curcumin treatment for inflammation would make sense? I also have Alzheimer’s (early onset) in my family.
   It’s difficult to say since we are not aware of much research in this area. Perhaps the use of anti-oxidants and natural anti-inflammatory supplements could be of benefit.

Inflammation1208-inflammation

Turmeric Root, Boswellia Resin, Ginger Root, Structured Water and 20% Alcohol.

Instructions:

Use 6-40 drops in mouth.. May be taken 8 times daily. Shake well. Store in cool dark place.

Special Precautions & Warnings:

May cause stomach upset. Do not use in large quantities. Consult doctor if you have gallstones. Keep out of reach of children.

Clin Nutr. 2011.Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis.
A double-blind intervention study has been conducted with two groups of non-smoking, un-treated sarcoidosis patients, matched for age and gender. One group was given 4 x 500 mg quercetin orally within 24 h, the other one placebo. Plasma malondialdehyde levels were used as marker of oxidative damage, plasma ratios of TNFα/IL-10 and IL-8/IL-10 as pro-inflammatory markers. Quercetin supplementation improved the antioxidant defense, indicated by the increased total plasma antioxidant capacity. Moreover, supplementation also reduced markers of oxidative stress and inflammation in the blood of sarcoidosis patients.

Respir Med. 2009. Antioxidant status associated with inflammation in sarcoidosis: a potential role for antioxidants. Department of Pharmacology and Toxicology, Maastricht University, The Netherlands.
Enhanced production of reactive oxygen species (ROS), capable of reducing endogenous defense levels and enhancing inflammation, is suggested to play a role in sarcoidosis. Antioxidant supplementation might offer protection against such ROS-mediated damage. Non-smoking sarcoidosis patients and healthy controls matched for age, gender and dietary behavior were enrolled. Measurements included assessment of total plasma antioxidant capacity, vitamin C, uric acid, glutathione, basal and LPS-induced levels of tumor necrosis factor alpha (TNFalpha), interleukin (IL)-8 and -10 as well as the effect of quercetin on these levels. Compared to their controls, the sarcoidosis patients displayed significantly lower total plasma antioxidant capacity, decreased levels of vitamin C, uric acid and glutathione and increased levels of basal TNFalpha and IL-8. Quercetin significantly decreased ex vivo LPS-induced TNFalpha- and IL-8 production in a concentration-dependent manner in both groups. Our results regarding the effect of quercetin on cytokine production imply that sarcoidosis patients might benefit from antioxidant supplementation not only by empowering the relatively low protection against ROS but also by reducing inflammation.

Quercetin/Nettle Plus 90 Tablets
Give your immune system the support it needs to stay balanced. Antioxidant Vitamin C is necessary for proper immune function, while the potent flavonoid quercetin helps to modulate immunity. Soothing magnesium, the enzyme bromelain and stinging nettle leaf help to keep the immune system on an even keel. Because more isn’t always better.   You can relax, knowing your immune system is balanced with Quercetin/Nettle Plus™.

Instructions: Three to six tablets daily, as a dietary supplement.

Other Ingredients: Cellulose, organic rice extract, and organic rice concentrate.

NO corn, soy, salt, yeast, gluten, milk & egg products, sugar, starch, or preservatives.

Special Precautions & Warnings:
Keep out of reach of children.

I would be grateful if I may have your thoughts on serrapeptase as a potential cure for sarcoidosis which has (so far) affected my lungs – I have lost over 60pct of lung capacity, aged 45, and very keen to find ways to push this condition into remission…. My doctors are telling me that there are no known ‘cures’ for my condition and cortico-steroids can assist in relieving the inflamatory symptoms, but clearly are not a long term solution… I have recently come across the “aden protocol” on the internet, which is promoting serrapeptase as a potential cure for this condition. Do you agree with this? What sort of dosage would you suggest?
   I have not seen any studies regarding this form of treatment so I do not know if this nutritional supplement would be effective.

intraMAX     w/serrapeptase

intraMAX® is an all-in-one liquid dietary supplement. This great-tasting natural formula contains over 415 essential ingredients derived from whole food sources such as fruits, vegetables, and herbs.

VITALZYM 180 Enteric capsules

Inflammation? You NEED Vitalzym!

Learn More About Vitalzym and Vitalzym Cardio

Serrapeptase Enzyme Fights Inflammation

Vitalzym Fights Inflammation

Our bodies have a love-hate relationship with inflammation. On the one hand, inflammation is a natural response, necessary to protect the body from invading organisms. On the other hand, inflammation can limit joint function, and destroy bone, cartilage and other articular structures.

An elusive goal of scientists and physicians has been to find a side-effect-free substance to reduce the pain and inflammation associated with fibrocystic breast disease, rheumatoid arthritis, idiopathic edema, carpal tunnel syndrome and post-operative swelling. It appears that the search may be nearing an end, thanks to an enzyme Serrapeptase produced by the larval form of the silk moth.

Serrapeptase is proving to be a superior alternative to the non-steroidal anti-inflammatory agents (NSAIDs) traditionally used to treat rheumatoid arthritis and osteoarthritis. Its uses have also been extended to the treatment of chronic sinusitis and postoperative inflammation, and some researchers believe the substance can play an important role in arterial plaque prevention and removal.

What is Internal Inflammation?

Inflammation can affect our internal organs, especially in cases of autoimmune disorders. This type of inflammation can cause many different symptoms, including pain; however, pain may not be a main symptom due to the fact that many of our organs contain only a few pain-sensitive nerves.

Symptoms may depend on which organs are affected.

  • Inflammation of the heart (myocarditis) may cause vague chest pain or fluid retention
  • Inflammation of the kidneys (nephritis) may cause high blood pressure or kidney failure
  • Inflammation of the large intestine (colitis) may cause cramps and diarrhea
  • Inflammation of the eye (iritis or uveitis) may cause pain or decreased vision
  • Inflammation of the muscles (polymyositis) may cause achiness or weakness
  • Inflammation of the blood vessels (vasculitis) may cause rash, headaches, or internal organ damage
  • Inflammation of the small tubes that transport air to the lungs (bronchiolitis) may cause shortness of breath similar to an asthma attack

As you can see, inflammation of the organs can be responsible for many different symptoms and conditions. Therefore, getting inflammation under control can be very important for overall health and proper organ function.

There are many medications available to help decrease pain and inflammation, such as Celebrex, aspirin, and ibuprofen, but they do not come without the risks of side effects. Using systemic enzymes like those in Vitalzym can naturally help reduce pain and inflammation without the use of prescription medications or over the counter pain relievers.

Inflammation – The Underlying Cause of Chronic Diseases

We are all familiar with the pain and inflammation that occurs when we are injured, have an infection, or have had surgery. But, how many of us are actually familiar with the body’s internal inflammatory process that exists in everyone? This internal inflammation can have a significant affect on the state of our health, leading to many chronic diseases.

According to an article in the New York Times titled Body’s Defender Goes on the Attack, “Scientists are coming to realize that inflammation may underlie many other common chronic diseases that come with aging, including atherosclerosis, diabetes, Alzheimer’s disease and osteoporosis. Inflammation is also implicated in asthma, cirrhosis of the liver, some bowel disorders, psoriasis, meningitis, cystic fibrosis, and even cancer.” 1

Serrapeptase: A Natural Anti-Inflammatory

Serrapeptase, also known as Serratia peptidase, is a proteolytic enzyme isolated from the non-pathogenic enterobacteria Serratia E15. When consumed in unprotected tablets or capsules, the enzyme is destroyed by acid in the stomach. However, enterically-coated tablets enable the enzyme to pass through the stomach unchanged, and be absorbed in the intestine. Serrapeptase is found in negligible amounts in the urine, suggesting that it is transported directly from the intestine into the bloodstream.

Clinical studies show that serrapeptase induces fibrinolytic, anti-inflammatory and anti-edemic (prevents swelling and fluid retention) activity in a number of tissues, and that its anti-inflammatory effects are superior to other proteolytic enzymes.

Besides reducing inflammation, one of serrapeptase’s most profound benefits is reduction of pain, due to its ability to block the release of pain-inducing amines from inflamed tissues.(18) Physicians throughout Europe and Asia have recognized the anti-inflammatory and pain-blocking benefits of this naturally occurring substance and are using it in treatment as an alternative to salicylates, ibuprofen and other NSAIDs.

In Germany and other European countries, serrapeptase is a common treatment for inflammatory and traumatic swellings, and much of the research that exists on this substance is of European origin. One double-blind study was conducted by German researchers to determine the effect of serrapeptase on post-operative swelling and pain. This study involved sixty-six patients who were treated surgically for fresh rupture of the lateral collateral ligament of the knee. On the third post-operative day, the group receiving serrapeptase exhibited a 50 percent reduction of swelling, compared to the controls. The patients receiving serrapeptase also became more rapidly pain-free than the controls, and by the tenth day, the pain had disappeared completely.

Inflammation and C-Reactive Proteins

C-reactive protein (CRP) is produced by the liver and is a clinical marker of general and/or cardiac-related inflammation. When internal inflammation is present, CRP levels can rise. According to Thomas “Tate” P. Erlinger, M.D., M.P.H., lead author of the study and an assistant professor of medicine at Johns Hopkins, “higher levels of C-reactive protein are linked to an increased risk of several apparently distinct, chronic diseases: heart disease, stroke, diabetes, and now colon cancer.” http://www.hopkinsmedicine.org/Press_releases/2004/02_10_04.html

The New York Times article continues to say “two large studies — one in men and one in women — have demonstrated that the higher a person’s C-reactive protein level, the greater the risk of a heart attack or stroke. Doctors nationwide are adding the C.R.P. test to cholesterol screening to assess people’s risk of atherosclerosis.1

CRP testing can be useful in assessing patient’s with3:

CRP can be used to screen otherwise healthy people for the following conditions. However, in these cases, the more sensitive high-sensitivity C-Reactive Protein test (hsCRP) will be ordered:

  • Coronary heart disease (CHD)
  • Cardiovascular disease

A health care professional may test someone for elevated CRP levels to check for internal inflammation or to help determine a person’s risk for heart disease. However, a low CRP level does not necessarily mean that inflammation is not present. For example, those with rheumatoid arthritis and lupus (inflammatory conditions) may or may not have increased levels of CRP; the reason for this is not known.

Reducing Inflammation and CRP Naturally

A primary goal for heart attack prevention, should be to keep inflammation to a minimum, says Dr. Peter Libby, chief of cardiovascular medicine at Brigham and Women’s hospital, and others.1

Research results regarding the connection between CRP, inflammation, and degenerative diseases are on the rise, which is leading many health care professionals to believe that lowering CRP levels can also help reduce internal inflammation and reduce the risk of chronic, degenerative diseases. Besides a healthy diet and exercise, systemic enzyme therapy has been shown to help reduce elevated CRP levels, inflammation, and symptoms associated with such conditions.
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Vitamin D

Q. I have followed you for years and would like to know if you have any new info on sarcoid and vitamin D. My daughter has lung sarcoidosis and was diagnosed 10 years ago. Should individuals with this condition avoid vitamin D completely?
   A. I have not seen enough data to have a strong opinion on this topic, but it seems for the moment that taking additional amounts through pills should be avoided due to potential hypercalcemia. Normal sun exposure seems to be acceptable.

Everyday Liquid Sunshine – Vitamin D3 Drops 1oz. start with 3 drops daily and ask you physician to monitor.

Call 1-541-791-8400 and ask for HCL  capsules and start with 400 mg with each meal 3 times daily after the first bottle order 500mg capsules.
Helps avoid hypercalcemia and the assimilation of Calcium.

Now you can safely try taking -1 or 2 and then maybe even 3 Calcium/Magnesium  tablets at bedtime
Nice Bones 250 Tablets
Monitor with your pyscian.

Sarcoidosis treatment
Sarcoidosis is a multisystem disorder of unknown causes. Less specific disabling symptoms, including fatigue and physical impairments, may have a major influence on the daily activities and the social and professional lives of the patients, resulting in a reduced quality of life.

The is no overall medical consensus regarding the treatment of this condition. Corticosteroids remain the cornerstone of therapy, but immunosuppressive, cytotoxic, and immunomodulatory agents have emerged as potential treatment options for patients failing or experiencing side effects from corticosteroids. Methotrexate has been evaluated, and there have been studies with leflunomide, azathioprine, antimalarial and antimicrobial agents, and tumor necrosis factor-alpha inhibitors.
   Patients with sarcoidosis are at risk for osteoporosis caused by glucocorticoid therapy.

  1. I have recently been diagnosed with pulmonary sarcoidosis stage 4 and am on a regiment of Prednisone and Plaquenil. Are you familiar with the Aden Dietary Protocol? Does Quercetin interfere with Plaquenil and or Prednisone.
       A. I am not very familiar with the Aden dietary protocol. I have not seen any studies regarding the interactions of these medications with quercetin.

Outlook for a patient
The progression varies among different patients, ranging from self-limited acute disease to a chronic debilitating disease that may result in death. Spontaneous remissions occur in about two thirds of patients, but 10-30% of patients have a more chronic or progressive course. Sarcoidosis often goes away on its own without treatment — usually within two to three years.

Depression
More than half of people with sarcoidosis have depression. Depression can affect one’s work, school studies, sleep, and even appetite. Depression is treatable. Medications and/or talk therapy are often helpful.

Gastrointestinal sarcoidosis
Gastrointestinal  tract involvement is rare.

Cardiac sarcoidosis
Cardiac involvement is a rare and potentially life-threatening complication. Infliximab may be considered as an alternative first-line therapy in sarcoidosis with serious organ involvement.

Drug cause of sarcoidosis
Etanercept therapy may trigger it. Interferon could also be a drug induced cause.

J Am Acad Dermatol. 2013. Cutaneous and pulmonary sarcoidosis-like reaction associated with ipilimumab.

Sarcoidosis natural treatment emails
Q. Do you know how to treat neuro sarcoidosis?
   A. I am not familiar with neurosarcoidosis treatment.

I found this site as I was searching the UNM in Albuquerque regarding the use of chlorambucil for sarcoidosis patients that are advanced in the disease and steroids are not an option. I am taking large doses of Benicar to help control the inflammation but my kidneys are in chronic renal failure. I am 54 and 3 years ago had a thyroidectomy and they found the sarcoidosis had destroyed it. Since then we have found it is very advanced. We tried steroids and I was not able to take it without severe adverse effects. I suffer from fevers and chilling, partial complex seizures, chronic pulmonary restrictive disease and i’m on 02, pain in all my bones, weak, lethargy, depression.
    Sorry, I am not familiar with this therapy and I do not have a contact source.

I am 38 yrs old. I was recently diagnosed with sarcoidosis and they currently have me taking Mycophenolate 500 MG Tablet (Cellcept). I would like to know if you know of any other alternative than the medication I am currently taking. I want to live a healthier life without taking medication that may cause me to get cancer.

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Overview

Certain herbs may be helpful in treating your sarcoidosis, which is an autoimmune disease that causes inflammation throughout the body. Although sarcoidosis can affect any organ in your body, it usually targets the lungs, skin and lymph nodes. Before taking herbs to help treat your sarcoidosis, talk with your doctor about possible side effects, proper dosage and potential drug interactions.

Turmeric

Turmeric, also known as Curcuma longa, is an herb that may be helpful in treating your sarcoidosis. According to the University of Maryland Medical Center, turmeric, a member of the ginger family, has been used for hundreds of years in both Ayurvedic medicine and traditional Chinese medicine as an anti-inflammatory to help treat numerous health problems. Turmeric is a perennial plant that grows in the tropical regions of South Asia, especially in India. Turmeric has a bitter, pungent taste and cooling and stimulating tendencies. It grows to a maximum height of about 6 feet. The rhizome, or underground stem of the plant, is used medicinally. Ed Smith, an herbalist and author of the book “Therapeutic Herb Manual,” states that turmeric is a potent antioxidant and anti-inflammatory that is helpful in treating various inflammatory disorders. If you have sarcoidosis or certain inflammatory skin disorders, you may benefit from taking this herb.
However, you should only take turmeric supplements after talking to your doctor.

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Dr. Sharol Tilgner, a naturopathic physician and author of the book “Herbal Medicine From the Heart of the Earth,” states that chamomile, also known as Matricaria recutita, is an anti-inflammatory, analgesic and antipyretic whose anti-inflammatory action can be partially attributed to its ability to inhibit arachidonic acid metabolism. Excessive amounts of arachidonic acid may increase your levels of inflammation, exacerbating sarcoidosis-related symptoms. Tilgner notes that chamomile, a member of the aster family, contains several anti-inflammatory constituents, including alpha bisabolol and chamazulene. Chamomile is a flowering plant native to Europe, north Africa and certain parts of Asia. Chamomile has a sweet and slightly bitter taste. The fresh or dried flowers of the plant are used by practitioners of botanical medicine to help treat many health problems, including sarcoidosis and other inflammatory conditions.

Chamomile Flower

Product Description

Ingredients: 

Chamomile Flower, Structured Water, 20% Alcohol. Vegetable Glycerin would replace the alcohol for alcohol free tinctures.

Instructions:

Use 6-30 drops in mouth, juice or water. May be taken 3 times daily. Shake well. Store in cool dark place.

Special Precautions & Warnings:

Keep out of reach of children.

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Goldenseal take 6- to 40 drops 3 to 6 times daily for 10 days.

Goldenseal is a small pant with jagged leaves, tiny flowers and raspberry-like fruit. Goldenseal thrives in rich soil and shady conditions in the northern United States and southeastern Ontario, although due to over-harvesting, most goldenseal is now grown on farms throughout the United States, especially in the Blue Ridge mountains of North Carolina. Goldenseal, also known as Hydrastis canadensis, belongs to the buttercup family, has a bitter taste, and possesses cooling and drying tendencies. The root of the plant is used for medicinal purposes. According to Tilgner, goldenseal is an alterative, or an herb that helps cleanse, revitalize and nourish your lymphatic fluids and cleanse your blood, which may be helpful in combating sarcoidosis-related symptoms, especially lymphatic system problems. If you are pregnant, cautions Tilgner, you should avoid taking this herb, due to its ability to stimulate your uterus. Consult your doctor for medical clearance before taking goldenseal supplements.

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Sarcoidosis is a name given to a group of symptoms pertaining to an autoimmune inflammatory disorder, which can lead to skin, lung, joint and kidney problems. Often times, sarcoidosis is associated with other chronic functional disorders like Fibromyalgia, chronic-fatigue-syndrome syndrome (CFS), depression, anxiety and hormonal imbalances. As a sarcoidosis speciaist in NJ, MD Wellness can help determine the cause of your symptoms and whether you can benefit from holistic treatment for sarcoidosis.

What Causes Sarcoidosis?

Once considered rare, sarcoidosis is now known to be common, affecting people all over the world.  The disease can affect people of any age, race and gender, however, it’s most common among adults between the ages of 20 and 40. In the U.S., African Americans have a much higher percentage of sarcoidosis than whites, and it’s usually much more serious in African Americans. Sarcoidosis is always multi-factorial but most often caused by the following conditions.

Excessive inflammation

Inflammation is the root cause of many chronic diseases and one of the most common causes of inflammation is immune system problems related to exposure to a water damaged building (WDB) like mold.

Sarcoidosis patients are frequently genetically predisposed to biotoxin illness like mold and Lyme disease. These harmful, common biological toxins can overstimulate your immune system and contribute to “autoimmune” disease

There are many inflammatory agents in our food supply that must be strictly avoided if you have sarcoidosis. You may be over-consuming carbohydrates, especially in the form of high fructose corn syrup (HFCS). You may also be eating too much fried foods, polyunsaturated vegetable oils, and food additives like nitrates, MSG and artificial sweeteners. These substances are highly toxic and cause inflammation.

Symptoms of low levels of vitamin D

There’s substantial evidence that sarcoidosis is one of the symptoms of low levels of vitamin D and vitamin D metabolism. Low levels of vitamin D can contribute to this disease, however many patients with sarcoidosis have hyperactive immune systems, which can cause excessive vitamin D.  Excess vitamin D will increase calcium levels in the cells, which will activate the nerve cells and cause excess inflammation, leading to more damage. Calcium deposits in tissues like lung and kidney are the hallmark of sarcoidosis. These calcium-laden lesions are named granulomas. Therefore, vitamin D supplementation should be very carefully monitored. Special blood tests looking at various forms of vitamin D should be utilized to determine your needs.

Food Allergies

If you have sarcoidosis, food Allergies may be contributing to your problems. You may also have a high incidence of bowel flora imbalances with excessive levels of pathogenic bacteria and low levels of beneficial bacteria. Often times, sarcoidosis patients also have leaky gut syndrome. These imbalances can over activate your immune system and add to inflammation.

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